Frequency-independent characteristics of high-frequency oscillations in epileptic and non-epileptic regions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00066032" target="_blank" >RIV/00159816:_____/17:00066032 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00094601

Result on the web

<a href="http://dx.doi.org/10.1016/j.clinph.2016.10.011" target="_blank" >http://dx.doi.org/10.1016/j.clinph.2016.10.011</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.clinph.2016.10.011" target="_blank" >10.1016/j.clinph.2016.10.011</a>

Result language

angličtina

Original language name

Frequency-independent characteristics of high-frequency oscillations in epileptic and non-epileptic regions

Original language description

OBJECTIVE: The purpose of the presented study is to determine whether there are frequency-independent high-frequency oscillation (HFO) parameters which may differ in epileptic and non-epileptic regions. METHODS: We studied 31 consecutive patients with medically intractable focal (temporal and extratemporal) epilepsies who were examined by either intracerebral or subdural electrodes. Automated detection was used to detect HFO. The characteristics (rate, amplitude, and duration) of HFO were statistically compared within three groups: the seizure onset zone (SOZ), the irritative zone (IZ), and areas outside the IZ and SOZ (nonSOZ/nonIZ). RESULTS: In all patients, fast ripples (FR) and ripples (R) were significantly more frequent and shorter in the SOZ than in the nonSOZ/nonIZ region. In the group of patients with favorable surgical outcomes, the relative amplitude of FR was higher in the SOZ than in the IZ and nonIZ/nonSOZ regions; in patients with poor outcomes, the results were reversed. The relative amplitude of R was significantly higher in the SOZ, with no difference between patients with poor and favorable surgical outcomes. CONCLUSIONS: FR are more frequent, shorter, and have higher relative amplitudes in the SOZ area than in other regions. The study suggests a worse prognosis in patients with higher amplitudes of FR outside the SOZ. SIGNIFICANCE: Various HFO parameters, especially of FR, differ in epileptic and non-epileptic regions. The amplitude and duration may be as important as the frequency band and rate of HFO in marking the seizure onset region or the epileptogenic area and may provide additional information on epileptogenicity.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical Neurophysiology

ISSN

1388-2457

e-ISSN

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Volume of the periodical

128

Issue of the periodical within the volume

1

Country of publishing house

IE - IRELAND

Number of pages

9

Pages from-to

106-114

UT code for WoS article

000396377300011

EID of the result in the Scopus database

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