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Infectious complications and immune/inflammatory response in cardiogenic shock patients: A prospective observational study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00066922" target="_blank" >RIV/00159816:_____/17:00066922 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/17:00096765 RIV/65269705:_____/17:00066922 RIV/00843989:_____/17:E0105904

  • Result on the web

    <a href="http://journals.lww.com/shockjournal/fulltext/2017/02000/Infectious_Complications_and_Immune_Inflammatory.7.aspx" target="_blank" >http://journals.lww.com/shockjournal/fulltext/2017/02000/Infectious_Complications_and_Immune_Inflammatory.7.aspx</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1097/SHK.0000000000000756" target="_blank" >10.1097/SHK.0000000000000756</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Infectious complications and immune/inflammatory response in cardiogenic shock patients: A prospective observational study

  • Original language description

    Introduction: Patients with cardiogenic shock (CS) are at a high risk of developing infectious complications; however, their early detection is difficult, mainly due to a frequently occurring noninfectious inflammatory response, which accompanies an extensivemyocardial infarction (MI) or a postcardiac arrest syndrome. The goal of our prospective study was to describe infectious complications in CS and the immune/inflammatory response based on a serial measurement of several blood-based inflammatory biomarkers. Methods: Eighty patients with CS were evaluated and their infections were monitored. Inflammatory markers (C-reactive protein, procalcitonin, pentraxin 3, presepsin) were measured seven times per week. The control groups consisted of 11 patients with ST segment elevation myocardial infarction without CS and without infection, and 22 patients in septic shock. Results: Infection was diagnosed in 46.3% of patients with CS; 16 patients developed an infection within 48 h. Respiratory infection was most common, occurring in 33 out of 37 patients. Infection was a significant or even the main reason of death only in 3.8% of all patients with CS, and we did not find statistically significant difference in 3-month mortality between group of patients with CS with and without infection. There was no statistically significant prolongation of the duration of mechanical ventilation associated with infection.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30221 - Critical care medicine and Emergency medicine

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Shock

  • ISSN

    1073-2322

  • e-ISSN

  • Volume of the periodical

    47

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    165-174

  • UT code for WoS article

    000392813300007

  • EID of the result in the Scopus database