CPAP with Pressure Relief during Exhalation (C-Flex ) is as Effective as CPAP in the Treatment of Obstructive Sleep Apnea

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067029" target="_blank" >RIV/00159816:_____/17:00067029 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.4172/2167-0277.1000268" target="_blank" >http://dx.doi.org/10.4172/2167-0277.1000268</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4172/2167-0277.1000268" target="_blank" >10.4172/2167-0277.1000268</a>

Result language

angličtina

Original language name

CPAP with Pressure Relief during Exhalation (C-Flex ) is as Effective as CPAP in the Treatment of Obstructive Sleep Apnea

Original language description

Purpose: Continuous positive airway pressure (CPAP) is the accepted therapy for obstructive sleep apnea (OSA). An expiratory pressure relief technology called C-Flex+ has been developed to improve the comfort of CPAP therapy. It provides a 2 mbar lower exhalation pressure and an additional flow-based pressure relief at the beginning of exhalation. The following study was conducted to investigate whether C-Flex+ was as effective as CPAP in treating OSA, and the patients&apos; preference. Methods: 60 newly diagnosed patients with OSA completed this double-blind controlled crossover-study. Patients were randomized to one night of C-Flex+ and one of CPAP under full attended polysomnography (PSG). A comfort visual analog scale (VAS) ranging from 0 to 10, with 10 being the highest comfort, was completed by all patients immediately after each PSG. Results: There was no significant difference between the therapy modes in the apnea/hypopnea index (median 1.5 events/hour (h) with C-Flex+ (interquartile range (IQR) 0.7 to 3.6) vs. 1.7 events/h with CPAP (IQR 0.8 to 3.8), p=0.178). The sleep efficiency, sleep architecture and nocturnal oxygenation were also comparable. Most patients preferred C-Flex+ over CPAP (65%, p&lt;0.001). C-Flex+ earned significantly higher ratings in the VAS (8.1 (7.2 to 9.0) vs. 7.0 (5.1 to 8.8), p&lt;0.001).

Czech name

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Czech description

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Type

J_ost - Miscellaneous article in a specialist periodical

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Sleep Disorders &amp; Therapy

ISSN

2167-0277

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

5

Pages from-to

1000268

UT code for WoS article

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EID of the result in the Scopus database

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