PET/CT imaging in polymyalgia rheumatica: praepubic F-18-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067558" target="_blank" >RIV/00159816:_____/17:00067558 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00098714 RIV/65269705:_____/17:00067558

Result on the web

<a href="https://www.degruyter.com/view/j/raon.2017.51.issue-1/raon-2017-0001/raon-2017-0001.xml" target="_blank" >https://www.degruyter.com/view/j/raon.2017.51.issue-1/raon-2017-0001/raon-2017-0001.xml</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/raon-2017-0001" target="_blank" >10.1515/raon-2017-0001</a>

Result language

angličtina

Original language name

PET/CT imaging in polymyalgia rheumatica: praepubic F-18-FDG uptake correlates with pectineus and adductor longus muscles enthesitis and with tenosynovitis

Original language description

Background. The role of F-18-fluorodeoxyglucose positron emission computed tomography (F-18-FDG PET/CT) is increasing in the diagnosis of polymyalgia rheumatica (PMR), one of the most common inflammatory rheumatic diseases. In addition to other locations, increased 18F-FDG accumulation has been detected in the praepubic region in some patients. However, a deeper description and pathophysiological explanation of this increased praepubic accumulation has been lacking. The aim of the presented study is to confirm a decrease in praepubic 18F-FDG accumulation in response to therapy and to describe potential correlations to other 18F-FDG PET/CT scan characteristics during the course of disease. As a secondary objective, we describe the pathological aspects of the observed praepubic 18F-FDG uptake. Patients and methods. A retrospective review of patients with newly suspected PMR undergoing baseline and follow up F-18-FDG PET/CT between February 2010 and March 2016 is given. Those with a visually detected presence of praepubic F-18-FDG accumulation were further analysed. The uptake was assessed visually and also semi-quantitatively in the defined region of interest by calculation of target-to-liver ratios. Other regions typical for PMR were systematically described as well (shoulders, hips, sternoclavicular joints, ischiogluteal bursae, spinous interspaces). Results. Twenty-three out of 89 screened patients (26%) presented with initial praepubic F-18-FDG PET/CT positivity, 15 of whom also underwent follow up 18F-FDG PET/CT examination. Five out of 15 patients presented with increased 18F-FDG accumulation in large arteries as a sign of giant cell arferitis. During follow up examination, decrease in 18F-FDG accumulation caused by therapeutic intervention was observed in all evaluated locations in all analysed patients and no new positivity was indicated, including periarticular, extraarticular tissues or target large vessels.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Radiology and Oncology

ISSN

1318-2099

e-ISSN

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Volume of the periodical

51

Issue of the periodical within the volume

1

Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

8-14

UT code for WoS article

000397080400002

EID of the result in the Scopus database

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