Atypical handedness in mesial temporal lobe epilepsy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067762" target="_blank" >RIV/00159816:_____/17:00067762 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/17:00099039

Result on the web

<a href="http://dx.doi.org/10.1016/j.yebeh.2017.01.034" target="_blank" >http://dx.doi.org/10.1016/j.yebeh.2017.01.034</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.yebeh.2017.01.034" target="_blank" >10.1016/j.yebeh.2017.01.034</a>

Result language

angličtina

Original language name

Atypical handedness in mesial temporal lobe epilepsy

Original language description

Objective: The main aim of our study was to investigate the handedness of patients with mesial temporal lobe epilepsy (MTLE). We also sought to identify clinical variables that correlated with left-handedness in this population. Methods: Handedness (laterality quotient) was assessed in 73 consecutive patients with MTLE associated with unilateral hippocampal sclerosis (HS) using the Edinburgh Handedness Inventory. Associations between rightand left-handedness and clinical variables were investigated. Results: We found that 54 (74.0%) patients were right-handed, and 19 (26%) patients were left-handed. There were 15 (36.6%) left-handed patients with left-sided seizure onset compared to 4 (12.5%) left-handed patients with right-sided seizure onset (p = 0.030). Among patients with left-sided MTLE, age at epilepsy onset was significantly correlated with handedness (8 years of age [median; min-max 0.5-17] in left-handers versus 15 years of age [median; min-max 3-30] in right-handers (p &lt; 0.001). Conclusions: Left-sided MTLE is associatedwith atypical handedness, especiallywhen seizure onset occurs during an active period of brain development, suggesting a bi-hemispheric neuroplastic process for establishing motor dominance in patients with early-onset left-sided MTLE.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Epilepsy &amp; Behavior

ISSN

1525-5050

e-ISSN

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Volume of the periodical

72

Issue of the periodical within the volume

JUL 2017

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

78-81

UT code for WoS article

000406321300014

EID of the result in the Scopus database

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