Admission systolic blood pressure and outcomes in large vessel occlusion strokes treated with endovascular treatment

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00068386" target="_blank" >RIV/00159816:_____/17:00068386 - isvavai.cz</a>

Result on the web

<a href="http://jnis.bmj.com/content/9/5/451?utm_source=TrendMD&utm_medium=cpc&utm_campaign=J_Neurointerv_Surg_TrendMD_1" target="_blank" >http://jnis.bmj.com/content/9/5/451?utm_source=TrendMD&utm_medium=cpc&utm_campaign=J_Neurointerv_Surg_TrendMD_1</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1136/neurintsurg-2016-012386" target="_blank" >10.1136/neurintsurg-2016-012386</a>

Result language

angličtina

Original language name

Admission systolic blood pressure and outcomes in large vessel occlusion strokes treated with endovascular treatment

Original language description

Background and purpose High admission blood pressure (BP) levels have been associated with lower recanalization rates after endovascular treatment (EVT) for patients with acute ischemic stroke (AIS) with emergent large vessel occlusion (ELVO). We sought to evaluate the association of admission BP with early outcomes in patients with ELVO treated with EVT. Methods Consecutive patients with AIS presenting with ELVO in a tertiary stroke center during a 4-year period were prospectively evaluated. Admission systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured using automated cuff recordings. A blinded neuroradiologist calculated the final infarct volume (FIV) using standardized ABC/2 methodology. A favorable functional outcome (FFO) at 3 months was defined as modified Rankin Scale score of 0-2. Results Our study population consisted of 116 patients with AIS (mean age 63 +/- 13 years, median NIH Stroke Scale score 17 points (IQR 14-21), median FIV 30 cm(3) (IQR 8-94)). Higher admission SBP correlated with higher FIV (r +0.225; p=0.020). Patients with FFO had lower admission SBP (151 +/- 24 mm Hg vs 165 +/- 28 mm Hg; p=0.010), while admission SBP levels were higher in patients who died during hospitalization ( 169 +/- 34 mm Hg vs 156 +/- 24 mm Hg; p=0.043). A 10 mm Hg increment in admission SBP was independently (p=0.010) associated with an increase of 12 cm3 in FIV (95% CI 3 to 21) in multiple linear regression models adjusting for potential confounders. A 10 mm Hg increment in admission SBP was independently (p=0.012) associated with a lower likelihood of FFO at 3 months (OR 0.64; 95% CI 0.45 to 0.91) in multiple logistic regression models adjusting for potential confounders. Conclusions Higher admission SBP is an independent predictor of increased FIV and lower likelihood of 3-month FFO in patients with ELVO treated with EVT.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of NeuroInterventional Surgery

ISSN

1759-8478

e-ISSN

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Volume of the periodical

9

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

5

Pages from-to

451-"+"

UT code for WoS article

000403148800012

EID of the result in the Scopus database

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