Development of methods for sleep disordered breathing to identify phenotypes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00068430" target="_blank" >RIV/00159816:_____/17:00068430 - isvavai.cz</a>
Result on the web
<a href="https://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=8026122" target="_blank" >https://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=8026122</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1109/EMBC.2017.8037185" target="_blank" >10.1109/EMBC.2017.8037185</a>
Alternative languages
Result language
angličtina
Original language name
Development of methods for sleep disordered breathing to identify phenotypes
Original language description
Sleep disordered breathing a very common disorder with prevalence rates of up to 49% in large epidemiological studies on subjects older than 40 years. A recent study showed that applying CPAP treatment to patients with sleep disordered breathing recruited by their number of apnea and hypopnea events alone, does improve sleepiness but does not improve overall cardiovascular mortality. Based on older large studies however it is knownthat sleep disordered breathing is a cardiovascular risk and that treatment lowers mortality and morbidity. These results appear to be contradictory. However, they might be explained if patient population investigated are carefully reviewed further, and if sleep apnea severity metrics are reconsidered. According to this, it appears that studies speak of different populations. Whereas epidemiological studies use sampled subjects willing to participate, earlier studies used patients contacting a sleep center with complaints and symptoms. In this paper two studies are presented with an assessment of anatomical metrics for upper airway morphology in order to derive parameters for better prediction. Different phenotypes can explain why some people benefit from treatment and others do not benefit equally. Therefore more than just counting apnea and hypopnea events is needed in order to identify patients at risk and patients who have a lower risk when treated. This will require large data set evaluations with hard outcome data.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
—
OECD FORD branch
10610 - Biophysics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
ISBN
978-1-5090-2809-2
ISSN
1094-687X
e-ISSN
neuvedeno
Number of pages
4
Pages from-to
1764-1767
Publisher name
IEEE
Place of publication
NEW YORK
Event location
SOUTH KOREA
Event date
Jul 11, 2017
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000427085302053