Heart rate variability is associated with outcome in spontaneous intracerebral hemorrhage

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00069025" target="_blank" >RIV/00159816:_____/18:00069025 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.jcrc.2018.08.033" target="_blank" >http://dx.doi.org/10.1016/j.jcrc.2018.08.033</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcrc.2018.08.033" target="_blank" >10.1016/j.jcrc.2018.08.033</a>

Result language

angličtina

Original language name

Heart rate variability is associated with outcome in spontaneous intracerebral hemorrhage

Original language description

Purpose: Autonomic imbalance as measured by heart rate variability (HRV) has been associated with poor outcome after stroke. Observations on HRV changes in intracerebral hemorrhage (ICH) are scarce. Here, we aimed to investigate HRV in ICH as compared to a control group and to explore associations with stroke severity, hemorrhage volume and outcome after ICH. Methods: We examined the autonomic modulation using frequency domain analysis of HRV during the acute phase of the ICH and in a healthy age- and hypertension-matched control group. Hematoma volume, intraventricular extension, initial stroke severity and baseline demographic, clinical parameters as well as mortality and functional outcome were included in the analysis. Results: 47 patients with ICH and 47 age- and hypertension matched controls were analyzed. ICH patients showed significantly lower total high frequency band (HF) and low frequency band (LF) powers (p = 0.01, p &lt; 0.001), higher normalized HF power (p= 0.03), and lower LF/HF ratio (p &lt; 0.001) as compared to the controls. Autonomic parameters showed associations with stroke severity (p= 0.004) and intraventricular involvement (p= 0.01) and predicted poor outcome independently (p= 0.02). Conclusions: Autonomic changes seems to be present in acute ICH and are associated with poor outcome independently. This may have future monitoring and therapeutic implications. (C) 2018 Published by Elsevier Inc.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30210 - Clinical neurology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Critical Care

ISSN

0883-9441

e-ISSN

—

Volume of the periodical

48

Issue of the periodical within the volume

SEP 2018

Country of publishing house

US - UNITED STATES

Number of pages

5

Pages from-to

85-89

UT code for WoS article

000449360800015

EID of the result in the Scopus database

2-s2.0-85052649654