Neovascularization after ischemic conditioning of the stomach and the influence of follow-up neoadjuvant chemotherapy thereon

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00069047" target="_blank" >RIV/00159816:_____/18:00069047 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/18:00106369 RIV/65269705:_____/18:00069047

Result on the web

<a href="https://www.termedia.pl/Neovascularization-after-ischemic-conditioning-of-the-stomach-and-the-influence-of-follow-up-neoadjuvant-chemotherapy-thereon,42,32837,1,1.html" target="_blank" >https://www.termedia.pl/Neovascularization-after-ischemic-conditioning-of-the-stomach-and-the-influence-of-follow-up-neoadjuvant-chemotherapy-thereon,42,32837,1,1.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5114/wiitm.2018.75907" target="_blank" >10.5114/wiitm.2018.75907</a>

Result language

angličtina

Original language name

Neovascularization after ischemic conditioning of the stomach and the influence of follow-up neoadjuvant chemotherapy thereon

Original language description

Introduction: Esophagectomy and reconstruction remain the optimal treatment for patients with resectable esophageal cancer. Neovascularization after ischemic conditioning of the stomach before esophagectomy is a laparoscopic procedure which may potentially reduce gastric conduit ischemia. Aim: To investigate the influence of ischemic conditioning on neovascularization along the greater curvature of the stomach and to explore the effect of neoadjuvant chemotherapy on neovascularization after ischemic conditioning. Material and methods: Staging laparoscopy was performed before the main resection procedure; during this procedure ischemic conditioning was performed. Samples taken from the human stomach were divided into 3 groups: group A - patients after ischemic conditioning with a delay of 30-45 days after left gastric artery (LGA) ligation (n = 4); group B - patients who were undergoing neoadjuvant chemotherapy with a delay of 90-140 days after left gastric artery ligation (n = 4); and control group C- patients without ischemic conditioning (n = 7). Results: After ischemic conditioning with a delay of 30-45 days, the count of neovessels along the greater curvature of the stomach increased from 5.4 +/- 0.7 in the control group to 17.5 +/- 0.9 in a low-power field of view (LPF) in group A and increased still further on average to 19.8 +/- 10.4 in group B. Conclusions: Left gastric artery ligation only is a sufficient procedure for ischemic conditioning of the stomach. Neovascularization along the greater curvature is a continuous process that depends on delay time. Neoadjuvant therapy has no influence on the effect of neovascularization.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30212 - Surgery

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Videosurgery and Other Miniinvasive Techniques

ISSN

1895-4588

e-ISSN

—

Volume of the periodical

13

Issue of the periodical within the volume

3

Country of publishing house

PL - POLAND

Number of pages

7

Pages from-to

299-305

UT code for WoS article

000443453800004

EID of the result in the Scopus database

2-s2.0-85053246547