A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00070711" target="_blank" >RIV/00159816:_____/19:00070711 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/19:00070711 RIV/00179906:_____/19:10409352
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0883944118313650?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0883944118313650?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jcrc.2019.02.015" target="_blank" >10.1016/j.jcrc.2019.02.015</a>
Alternative languages
Result language
angličtina
Original language name
A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit
Original language description
Purpose: To investigate age-related differences in outcomes of critically ill patients with sepsis around the world. Methods: We performed a secondary analysis of data from the prospective ICON audit, in which all adult ( >16 years ) patients admitted to participating ICUs between May 8 and 18, 2012, were included, except admissions for routine postoperative observation. For this sub-analysis, the 10,012 patients with completed age data were included. They were divided into five age groups - <= 50, 51-60, 61-70, 71-80, >80 years. Sepsis was defined as infection plus at least one organ failure. Results: A total of 2963 patients had sepsis, with similar proportions across the age groups (<= 50 = 25.2%: 51-60 = 30.3%; 61-70 = 32.8%; 71-80 = 30.7%; >80 = 30.9%). Hospital mortality increased with age and in patients >80 years was almost twice that of patients <= 50 years (493% vs 25.2%, p < .05). The maximum rate of increase in mortality was about 0.75% per year, occurring between the ages of 71 and 77 years. In multilevel analysis, age > 70 years was independently associated with increased risk of dying. Conclusions: The odds for death in ICU patients with sepsis increased with age with the maximal rate of increase occurring between the ages of 71 and 77 years. (C) 2019 Elsevier Inc. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30221 - Critical care medicine and Emergency medicine
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Critical Care
ISSN
0883-9441
e-ISSN
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Volume of the periodical
51
Issue of the periodical within the volume
JUNE 2019
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
122-132
UT code for WoS article
000468412000023
EID of the result in the Scopus database
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