Can Nutrition or Inflammation Moderate the Age-Cognition Association Among Older Adults?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00071050" target="_blank" >RIV/00159816:_____/19:00071050 - isvavai.cz</a>

Result on the web

<a href="https://academic.oup.com/psychsocgerontology/article/74/2/193/3800357" target="_blank" >https://academic.oup.com/psychsocgerontology/article/74/2/193/3800357</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/geronb/gbx054" target="_blank" >10.1093/geronb/gbx054</a>

Result language

angličtina

Original language name

Can Nutrition or Inflammation Moderate the Age-Cognition Association Among Older Adults?

Original language description

Objectives Previous research has shown that nutrition can influence cognitive abilities in older adults. We examined whether nutritional factors or inflammatory biomarkers moderate the age-cognition association. Method Analyses included 1,308 participants (age 60) from the National Health and Nutrition Examination Survey III. Macronutrients (% of calories from fat, protein, and carbohydrates), micronutrients/amino acids (blood serum values: Vitamins B12(,) C, D, E, folate, iron, homocysteine, and -carotene), and inflammatory biomarkers (serum C-reactive protein, plasma fibrinogen, and serum ferritin) were examined as moderators with cognition. Cognition was measured by six tasks: immediate and delayed story recall, immediate and delayed word memory, digit subtraction, and questions about place/orientation. Results Higher values of serum folate were significantly associated with better cognitive scores. Specifically, the interaction between age-cognition and folate indicated the associations of higher age and lower global cognition and lower immediate story recall were weaker in those with higher folate values (p&apos;s &lt; .05). A significant interaction between age and plasma fibrinogen indicated that the association between age and worse digit subtraction was stronger with values &gt;3.1 g/L. Discussion Folate and fibrinogen were significant moderators between age and cognition. Further research into the relationship between nutrition, inflammation, and cognitive aging is needed.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30227 - Geriatrics and gerontology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journals of Gerontology series B - Psychological Sciences and Social Sciences

ISSN

1079-5014

e-ISSN

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Volume of the periodical

74

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

193-201

UT code for WoS article

000462568900001

EID of the result in the Scopus database

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