Options for modeling the respiratory system: inserts, scaffolds and microfluidic chips
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00071085" target="_blank" >RIV/00159816:_____/19:00071085 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/19:00108503
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1359644618304458" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1359644618304458</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.drudis.2019.03.006" target="_blank" >10.1016/j.drudis.2019.03.006</a>
Alternative languages
Result language
angličtina
Original language name
Options for modeling the respiratory system: inserts, scaffolds and microfluidic chips
Original language description
The human respiratory system is continuously exposed to varying levels of hazardous substances ranging from environmental toxins to purposely administered drugs. If the noxious effects exceed the inherent regenerative capacity of the respiratory system, injured tissue undergoes complex remodeling that can significantly affect lung function and lead to various diseases. Advanced near-to-native in vitro lung models are required to understand the mechanisms involved in pulmonary damage and repair and to reliably test the toxicity of compounds to lung tissue. This review is an overview of the development of in vitro respiratory system models used for study of lung diseases. It includes discussion of using these models for environmental toxin assessment and pulmonary toxicity screening.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/NV16-31501A" target="_blank" >NV16-31501A: Engineering of epithelia: Cells and protocols for regenerative medicine</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
DRUG DISCOVERY TODAY
ISSN
1359-6446
e-ISSN
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Volume of the periodical
24
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
971-982
UT code for WoS article
000467511200007
EID of the result in the Scopus database
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