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MyocardialT(1)mapping using SMART(1)Map and MOLLI mapping in asymptomatic patients with recent extracardiac sarcoidosis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00073093" target="_blank" >RIV/00159816:_____/20:00073093 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/20:00116191 RIV/65269705:_____/20:00073093

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1002/nbm.4388" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/nbm.4388</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/nbm.4388" target="_blank" >10.1002/nbm.4388</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    MyocardialT(1)mapping using SMART(1)Map and MOLLI mapping in asymptomatic patients with recent extracardiac sarcoidosis

  • Original language description

    Introduction Sarcoidosis is a systemic granulomatous disease affecting in particular the respiratory tract. Cardiac magnetic resonance (CMR), including a measurement ofT(1)relaxation time, could potentially detect early stadia of sarcoidosis of the heart. The study aims to assessT(1)mapping in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and twenty patients with extracardiac sarcoidosis and without any heart disease history were included. One hundred and thirteen of them underwent a CMR examination. The mean time from the diagnosis of sarcoidosis was 0.8 (0.2-3.3) years. Cine images for the assessment of left ventricular (LV) functional parameters and pre- and post-contrast saturation method using adaptive recovery times for cardiacT(1)mapping (SMART(1)Map) and modified Look-Locker inversion recovery (MOLLI) images were acquired for the assessment of nativeT(1)relaxation time and extracellular volume (ECV). The measured parameters were compared between sarcoidosis patients and 22 controls. Results The sarcoidosis patients had normal global and regional systolic LV function-LV ejection fraction 65 +/- 5% versus 66 +/- 7% (pNS). The mean nativeT(1)relaxation times were not prolonged-1465 +/- 93 ms versus 1480 +/- 88 ms (pNS) measured by SMART(1)Map and 1317 +/- 60 ms versus 1313 +/- 83 ms (pNS) measured using a MOLLI sequence. Similarly, the mean ECV values did not increase-16.9 +/- 3.9% versus 17.9 +/- 3.7% (pNS) measured by SMART(1)Map and 30.9 +/- 2.9% versus 31.6 +/- 8.3% (pNS) measured using a MOLLI sequence. Conclusion Myocardial nativeT(1)relaxation times were not prolonged and ECV was not increased in asymptomatic patients with extracardiac sarcoidosis.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10610 - Biophysics

Result continuities

  • Project

    <a href="/en/project/LQ1605" target="_blank" >LQ1605: Translational Medicine</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    NMR in biomedicine

  • ISSN

    0952-3480

  • e-ISSN

  • Volume of the periodical

    33

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    "e4388"

  • UT code for WoS article

    000555266900001

  • EID of the result in the Scopus database

    2-s2.0-85089002383