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Mozart effect in epilepsy: Why is Mozart better than Haydn? Acoustic qualities-based analysis of stereoelectroencephalography

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00074714" target="_blank" >RIV/00159816:_____/21:00074714 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14740/21:00120200

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1111/ene.14758" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/ene.14758</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/ene.14758" target="_blank" >10.1111/ene.14758</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Mozart effect in epilepsy: Why is Mozart better than Haydn? Acoustic qualities-based analysis of stereoelectroencephalography

  • Original language description

    Background and purpose We aimed to confirm the Mozart effect in epileptic patients using intracerebral electroencephalography recordings and the hypothesis that the reduction of epileptiform discharges (EDs) can be explained by the music&apos;s acoustic properties. Methods Eighteen epilepsy surgery candidates were implanted with depth electrodes in the temporal medial and lateral cortex. Patients listened to the first movement of Mozart&apos;s Sonata for Two Pianos K. 448 and to the first movement of Haydn&apos;s Symphony No. 94. Musical features from each composition with respect to rhythm, melody, and harmony were analyzed. Results Epileptiform discharges in intracerebral electroencephalography were reduced by Mozart&apos;s music. Listening to Haydn&apos;s music led to reduced EDs only in women; in men, the EDs increased. The acoustic analysis revealed that nondissonant music with a harmonic spectrum and decreasing tempo with significant high-frequency parts has a reducing effect on EDs in men. To reduce EDs in women, the music should additionally be gradually less dynamic in terms of loudness. Finally, we were able to demonstrate that these acoustic characteristics are more dominant in Mozart&apos;s music than in Haydn&apos;s music. Conclusions We confirmed the reduction of intracerebral EDs while listening to classical music. An analysis of the musical features revealed that the acoustic characteristics of music are responsible for suppressing brain epileptic activity. Based on our study, we suggest studying the use of musical pieces with well-defined acoustic properties as an alternative noninvasive method to reduce epileptic activity in patients with epilepsy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30210 - Clinical neurology

Result continuities

  • Project

    <a href="/en/project/NV17-32292A" target="_blank" >NV17-32292A: Lesion detection in non-lesional epilepsies using multimodal imaging methods</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Neurology

  • ISSN

    1351-5101

  • e-ISSN

  • Volume of the periodical

    28

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    1463-1469

  • UT code for WoS article

    000621067800001

  • EID of the result in the Scopus database