Altered Spatiotemporal Dynamics of the Resting Brain in Mild Cognitive Impairment with Lewy Bodies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00074915" target="_blank" >RIV/00159816:_____/21:00074915 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/21:00120175
Result on the web
<a href="https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.28741" target="_blank" >https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.28741</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/mds.28741" target="_blank" >10.1002/mds.28741</a>

Result language
angličtina
Original language name
Altered Spatiotemporal Dynamics of the Resting Brain in Mild Cognitive Impairment with Lewy Bodies
Original language description
Background Electrophysiological markers of prodromal dementia with Lewy bodies were described in the spectral domain. The sub-second temporal resolution may provide additional information. Objective To evaluate electroencephalography (EEG) microstates in patients with mild cognitive impairment with Lewy bodies and to assess the association between their temporal dynamics and the spectral marker. Methods Temporal parameters of microstates were compared between 21 patients with mild cognitive impairment with Lewy bodies and 21 healthy controls. The dominant alpha frequency was correlated with microstate parameters. Results Microstates A-D showed higher occurrence in the patient group. Microstate B additionally revealed shorter mean duration and increased time coverage; its occurrence correlated with the dominant alpha frequency in the patient group. Conclusions Temporal dynamics of all EEG microstates were altered in medication-naive subjects with prodromal dementia with Lewy bodies. Longitudinal follow-up may reveal how EEG microstates reflect progression of brain function deficits and effects of treatment manipulations. (c) 2021 International Parkinson and Movement Disorder Society
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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