Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00075809" target="_blank" >RIV/00159816:_____/23:00075809 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/23:00129952 RIV/61989592:15110/23:73612540 RIV/00098892:_____/23:10157727
Result on the web
<a href="https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3084" target="_blank" >https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3084</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2021.062" target="_blank" >10.5507/bp.2021.062</a>
Alternative languages
Result language
angličtina
Original language name
Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx
Original language description
Aims. The objective of this study was to compare bone invasion type with histopathological, clinical and immunohis Methods. The study included 49 patients who were treated for oral squamous cell carcinoma. Of which, 30 patients, with presence of bone invasion on histopathology, were divided according to the type of bone invasion (erosive, infiltrative, mixed). Each invasion type was compared to microvascular density using the CD34 marker. Results. The bone invasion was observed in 30 out of 49 patients (61.22%). On McNemar's test, statistically significant association was observed between bone invasion types and histopathological grade. In contrast, no significant correlation was observed between bone invasion type, and tumour volume or nodal metastases. In tumours with bone invasion of the infiltrative type, higher frequency of locoregional relapses was observed. The 5-year survival, since diagnosis, was approximately 60% in the erosive group, 40% in the mixed group, and merely 15% in the infiltrative group. Conclusion. Peritumoural microvascular density was not significantly related to bone invasion types. Whereas, a significantly higher intratumoural microvascular density was observed in infiltrative type of the bone invasion, when compared to the erosive and mixed type.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30100 - Basic medicine
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical papers
ISSN
1213-8118
e-ISSN
1804-7521
Volume of the periodical
167
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
139-144
UT code for WoS article
000731344000001
EID of the result in the Scopus database
2-s2.0-85162843197