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Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00075809" target="_blank" >RIV/00159816:_____/23:00075809 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/23:00129952 RIV/61989592:15110/23:73612540 RIV/00098892:_____/23:10157727

  • Result on the web

    <a href="https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3084" target="_blank" >https://biomed.papers.upol.cz/corproof.php?tartkey=bio-000000-3084</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2021.062" target="_blank" >10.5507/bp.2021.062</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Importance of evaluation of bone invasion type in squamous cell carcinomas of the oral cavity and oropharynx

  • Original language description

    Aims. The objective of this study was to compare bone invasion type with histopathological, clinical and immunohis Methods. The study included 49 patients who were treated for oral squamous cell carcinoma. Of which, 30 patients, with presence of bone invasion on histopathology, were divided according to the type of bone invasion (erosive, infiltrative, mixed). Each invasion type was compared to microvascular density using the CD34 marker. Results. The bone invasion was observed in 30 out of 49 patients (61.22%). On McNemar&apos;s test, statistically significant association was observed between bone invasion types and histopathological grade. In contrast, no significant correlation was observed between bone invasion type, and tumour volume or nodal metastases. In tumours with bone invasion of the infiltrative type, higher frequency of locoregional relapses was observed. The 5-year survival, since diagnosis, was approximately 60% in the erosive group, 40% in the mixed group, and merely 15% in the infiltrative group. Conclusion. Peritumoural microvascular density was not significantly related to bone invasion types. Whereas, a significantly higher intratumoural microvascular density was observed in infiltrative type of the bone invasion, when compared to the erosive and mixed type.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30100 - Basic medicine

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical papers

  • ISSN

    1213-8118

  • e-ISSN

    1804-7521

  • Volume of the periodical

    167

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    139-144

  • UT code for WoS article

    000731344000001

  • EID of the result in the Scopus database

    2-s2.0-85162843197