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Heart Failure Treatment in 2023: Is There a Place for Lipid Lowering Therapy?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00079465" target="_blank" >RIV/00159816:_____/23:00079465 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/23:00133673

  • Result on the web

    <a href="https://link.springer.com/article/10.1007/s11883-023-01166-3" target="_blank" >https://link.springer.com/article/10.1007/s11883-023-01166-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s11883-023-01166-3" target="_blank" >10.1007/s11883-023-01166-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Heart Failure Treatment in 2023: Is There a Place for Lipid Lowering Therapy?

  • Original language description

    Purpose of ReviewAn evidence for lipid lowering therapy in heart failure is briefly summarized in this review.Recent FindingsHeart failure therapy is based on recent guidelines for diagnosis and treatment of acute and chronic heart failure. The question of the importance of hypolipidemic treatment in heart failure remains insufficiently answered. We still rely only on results of two randomized controlled trials that did not show significant benefit of statins on mortality in these patients. In contrast, some meta-analysis, prospective or retrospective cohorts, found some positive effects of this therapy. Recently, the role of inflammation and the possibility of its influence by hypolipidemics have been discussed. PCSK9 inhibitors, new lipid lowering drugs, are very effective in LDL-cholesterol lowering and atherosclerotic cardiovascular diseases prevention. The role of PCSK9 inhibitors in heart failure treatment is investigated.SummaryBased on current knowledge, hypolipidemics are not generally recommended in heart failure therapy, unless there is another indication for their use.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

    <a href="/en/project/LX22NPO5104" target="_blank" >LX22NPO5104: National Institute for Research of Metabolic and Cardiovascular Diseases</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Current Atherosclerosis Reports

  • ISSN

    1523-3804

  • e-ISSN

    1534-6242

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    957-964

  • UT code for WoS article

    001118155800003

  • EID of the result in the Scopus database