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Severe sleep apnea as a predictor of failure to respond to cardiac resynchronization therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F23%3A00079644" target="_blank" >RIV/00159816:_____/23:00079644 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S0147956323000183?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0147956323000183?via%3Dihub</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.hrtlng.2023.01.018" target="_blank" >10.1016/j.hrtlng.2023.01.018</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Severe sleep apnea as a predictor of failure to respond to cardiac resynchronization therapy

  • Original language description

    Background: The response to cardiac resynchronization therapy (CRT) is suboptimal in one-third of patients. Objectives: The study aimed to evaluate the impact of sleep-disordered breathing (SDB) on the CRT-induced left ventricular (LV) reverse remodeling and response for CRT in patients with ischemic congestive heart fail-ure (CHF).Methods: A total of 37 patients aged 65.43 years (SD 6.05), seven of whom were females, were treated with CRT according to class I European Society of Cardiology recommendations. Clinical evaluation, polysomnog-raphy, and contrast echocardiography were performed twice during the six-month follow-up (6M-FU) to assess the effect of CRT.Results: In 33 patients (89.1%), sleep-disordered breathing (SDB), predominantly central sleep apnea (70.3%) was observed. This include nine patients (24.3%) with an apnea-hypopnea index (AHI) of &gt;30 events/hour. During the 6M-FU, 16 patients (47.1%) responded to CRT by reducing LV end-systolic volume index (LVESVi) by &gt;15%. We stated a directly proportional linear relationship between AHI value and LV volume: LVESVi p = 0.004, and LV end-diastolic volume index p = 0.006.Conclusions: Pre-existing severe SDB can impair the LV volumetric response to CRT even in an optimally selected group with class I indications for resynchronization, which may have an impact on long-term prog-nosis.(c) 2023 Published by Elsevier Inc.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Heart &amp; Lung

  • ISSN

    0147-9563

  • e-ISSN

    1527-3288

  • Volume of the periodical

    59

  • Issue of the periodical within the volume

    MAY 2023

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    102-108

  • UT code for WoS article

    000942538300001

  • EID of the result in the Scopus database