Influence of metabolic state and body composition on the action of pharmacological treatment of migraine

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00081200" target="_blank" >RIV/00159816:_____/24:00081200 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/24:00135905

Result on the web

<a href="https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-024-01724-3" target="_blank" >https://thejournalofheadacheandpain.biomedcentral.com/articles/10.1186/s10194-024-01724-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s10194-024-01724-3" target="_blank" >10.1186/s10194-024-01724-3</a>

Result language

angličtina

Original language name

Influence of metabolic state and body composition on the action of pharmacological treatment of migraine

Original language description

Migraine is a disabling neurovascular disorder among people of all ages, with the highest prevalence in the fertile years, and in women. Migraine impacts the quality of life of affected individuals tremendously and, in addition, it is associated with highly prevalent metabolic diseases, such as obesity, diabetes mellitus and thyroid dysfunction. Also, the clinical response to drugs might be affected in patients with metabolic disease due to body composition and metabolic change. Therefore, the efficacy of antimigraine drugs could be altered in patients with both migraine and metabolic disease. However, knowledge of the pharmacology and the related clinical effects of antimigraine drugs in patients with metabolic disease are limited. Therefore, and given the clinical relevance, this article provides a comprehensive overview of the current research and hypotheses related to the influence of metabolic state and body composition on the action of antimigraine drugs. In addition, the influence of antimigraine drugs on metabolic functioning and, vice versa, the influence of metabolic diseases and its hormonal modulating medication on migraine activity is outlined. Future exploration on personalizing migraine treatment to individual characteristics is necessary to enhance therapeutic strategies, especially given its increasing significance in recent decades.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30200 - Clinical medicine

Project

<a href="/en/project/LM2023049" target="_blank" >LM2023049: Czech National Node of the European Clinical Research Infrastructures Network</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Headache and Pain

ISSN

1129-2369

e-ISSN

1129-2377

Volume of the periodical

25

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

22

Pages from-to

20

UT code for WoS article

001160025300001

EID of the result in the Scopus database

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