High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00081488" target="_blank" >RIV/00159816:_____/24:00081488 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/24:00136522

Result on the web

<a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11370809/" target="_blank" >https://pmc.ncbi.nlm.nih.gov/articles/PMC11370809/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/brain/awae159" target="_blank" >10.1093/brain/awae159</a>

Result language

angličtina

Original language name

High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?

Original language description

Despite advances in understanding the cellular and molecular processes underlying memory and cognition, and recent successful modulation of cognitive performance in brain disorders, the neurophysiological mechanisms remain underexplored. High frequency oscillations beyond the classic electroencephalogram spectrum have emerged as a potential neural correlate of fundamental cognitive processes.High frequency oscillations are detected in the human mesial temporal lobe and neocortical intracranial recordings spanning gamma/epsilon (60-150 Hz), ripple (80-250 Hz) and higher frequency ranges. Separate from other non-oscillatory activities, these brief electrophysiological oscillations of distinct duration, frequency and amplitude are thought to be generated by coordinated spiking of neuronal ensembles within volumes as small as a single cortical column. Although the exact origins, mechanisms and physiological roles in health and disease remain elusive, they have been associated with human memory consolidation and cognitive processing.Recent studies suggest their involvement in encoding and recall of episodic memory with a possible role in the formation and reactivation of memory traces. High frequency oscillations are detected during encoding, throughout maintenance, and right before recall of remembered items, meeting a basic definition for an engram activity. The temporal coordination of high frequency oscillations reactivated across cortical and subcortical neural networks is ideally suited for integrating multimodal memory representations, which can be replayed and consolidated during states of wakefulness and sleep. High frequency oscillations have been shown to reflect coordinated bursts of neuronal assembly firing and offer a promising substrate for tracking and modulation of the hypothetical electrophysiological engram. Kucewicz et al. review the role of high frequency gamma and ripple oscillations in human memory and cognition, and propose that these fast activity bursts track coordinated firing of neuronal assemblies across the brain during the formation and recall of memory traces.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Brain

ISSN

0006-8950

e-ISSN

1460-2156

Volume of the periodical

147

Issue of the periodical within the volume

9

Country of publishing house

US - UNITED STATES

Number of pages

17

Pages from-to

2966-2982

UT code for WoS article

001293707300001

EID of the result in the Scopus database

—