Exploring new galaxies: Perspectives on the discovery of novel PET-degrading enzymes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00081594" target="_blank" >RIV/00159816:_____/24:00081594 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/24:00135422
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S0926337323010470" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0926337323010470</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.apcatb.2023.123404" target="_blank" >10.1016/j.apcatb.2023.123404</a>
Alternative languages
Result language
angličtina
Original language name
Exploring new galaxies: Perspectives on the discovery of novel PET-degrading enzymes
Original language description
Polyethylene terephthalate (PET) is a widely used polyester due to its beneficial material properties and low cost. However, PET contributes significantly to the growing problem of plastic waste pollution. Enzymatic PET recycling has emerged as a promising alternative to conventional mechanical and chemical recycling methods. While many PET hydrolases - belonging to the alpha/beta-hydrolase fold superfamily - have been discovered, the wild -type enzymes obtained from natural sources are not optimal for industrial conditions and need to be optimized through rational design or directed evolution to improve their efficiency and stability. This Perspective sum-marizes case studies of engineered PET hydrolases and proposes a workflow that tightly integrates a variety of in silico and high-throughput approaches for biochemical and structural characterization to accelerate the discovery of PET-degrading enzymes, also with novel structural scaffolds. These biocatalysts could be candidates for developing further innovative plastic recycling techniques.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
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Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
APPLIED CATALYSIS B-ENVIRONMENTAL
ISSN
0926-3373
e-ISSN
1873-3883
Volume of the periodical
342
Issue of the periodical within the volume
MAR
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
16
Pages from-to
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UT code for WoS article
001110359200001
EID of the result in the Scopus database
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