CT-derived adipose tissue characteristics and TAVI all-cause mortality and complications: a systematic review

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F25%3A00082408" target="_blank" >RIV/00159816:_____/25:00082408 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/25:00141060 RIV/61988987:17110/25:A2603DD4 RIV/00216208:11120/25:43928380 RIV/61989100:27240/25:10257798
Result on the web
<a href="https://link.springer.com/article/10.1186/s40001-025-02587-3" target="_blank" >https://link.springer.com/article/10.1186/s40001-025-02587-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s40001-025-02587-3" target="_blank" >10.1186/s40001-025-02587-3</a>

Result language
angličtina
Original language name
CT-derived adipose tissue characteristics and TAVI all-cause mortality and complications: a systematic review
Original language description
Transcatheter Aortic Valve Implantation (TAVI) has revolutionized severe aortic stenosis treatment, but risk stratification remains challenging. This systematic review examined the association between computed tomography (CT)-derived adipose tissue parameters and TAVI outcomes. We searched major databases for studies on visceral (VAT), subcutaneous (SAT), and intramuscular (IMAT) adipose tissue parameters and post-TAVI outcomes. Fourteen studies (9692 patients) were included. Higher SAT area/volume was consistently associated with better survival (5 studies, HR range: 0.83-2.77, p < 0.05). Lower SAT and VAT density also correlated with better survival (5 and 4 studies, respectively, HR range: 1.31-1.46, p < 0.05). VAT area showed mixed results. A VAT:SAT ratio < 1 was associated with better cardiovascular outcomes in one study. Lower IMAT index correlated with shorter hospital stays in a single study. This review reveals complex relationships between adipose tissue parameters and TAVI outcomes. Lower adipose tissue density and higher subcutaneous adiposity were most consistently associated with better outcomes. These findings suggest that detailed analysis of adipose tissue characteristics may enhance risk stratification in TAVI candidates.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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