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Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F08%3A00001098" target="_blank" >RIV/00179906:_____/08:00001098 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/08:00106758

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Non invasive in vivo assessment of the skeletal muscle and small intestine serous surface microcirculation in rat : sidestream dark-field (SDF) imaging

  • Original language description

    The pathophysiology of microcirculation is intensively investigated to understand disease development at the microscopic level. The goal of this experimental study was to describe basic microcirculatory parameters of skeletal muscle and ileal serous surface microcirculation in the rat using SDF imaging and to standardize the technical aspects of the protocol. There was no statistically significant difference in mean values of FCD obtained from the muscle (P = 0.273) in contrast to ileal serous surface where the difference was statistically significant (P = 0.036). Neither on the muscle surface (P = 0.739) nor on ileal serous surface (P = 0.659) statistically significant differences in small vessels percentage was detected. Our study has shown that SDFimaging represents promising technology for experimental and clinical studies.

  • Czech name

    Posouzení mikrocirkulace svalu a střeva u potkana

  • Czech description

    Experimentální práce zamřená na vyhodnocení mikrocirkulace kosterního svalu a střevní stěny potkana metodou Sidestream dark-field (SDF) imaging s důrazem na standardizaci metodiky a porovnání výsledků s dostupnými daty z validačních studií. Nebyl zjištěnstatisticky významný interindividuální rozdíl v hodnotách FCD kosterního svalu na rozdíl od hodnot FCD střevní stěny, kde byl zjištěn rozdíl na hranici statistické významnosti. Studie dokumentuje možnost využití SDF technologie jako spolehlivé metody při zobrazování změn mikrocirkulace s velkým potenciálem využití v experimentu i klinické praxi.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Research

  • ISSN

    0862-8408

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

  • UT code for WoS article

    000257270900006

  • EID of the result in the Scopus database