Failure of therapy or resistance to antiplatelet drugs?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F09%3A00201678" target="_blank" >RIV/00179906:_____/09:00201678 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/09:00208673

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Failure of therapy or resistance to antiplatelet drugs?

Original language description

Even though the efficacy of acetylsalicylic acid (ASA) and clopidogrel has been documented in patients with acute and chronic coronary artery disease (CAD),many patients develop thrombotic cardiovascular complications despite dual antiplatelet therapy due to nonresponsiveness or partial responsiveness. The phenomenon of resistance to antiplatelet therapy remains incompletely defined, influenced as it is by a variety of genetic, cellular, and clinical factors. In conclusion, although clinical guidelinesstill do not support routine screening for antiplatelet drug resistance (because a standard laboratory assay is still lacking), there is mounting evidence for the need to correlate the laboratory and clinical parameters of platelet activity assessment indifferent clinical scenarious.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/NR9174" target="_blank" >NR9174: Determination and significance of resistance to antiplatelet therapy</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cor et Vasa

ISSN

0010-8650

e-ISSN

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Volume of the periodical

51

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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