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HPLC method for simultaneous determination of retinoids and tocopherols in human serum for monitoring of anticancer therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F09%3A00201854" target="_blank" >RIV/00179906:_____/09:00201854 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/09:00208914 RIV/00216208:11160/09:00210072 RIV/61989592:15110/09:10223874

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    HPLC method for simultaneous determination of retinoids and tocopherols in human serum for monitoring of anticancer therapy

  • Original language description

    A simple and rapid HPLC method requiring small volumes (250 uL) of human serum after C18 SPE sample preparation was developed using monolithic technology for simultaneous determination of all-trans-retinoic acid, 13-cis-retinoic acid, retinol, gamma- and alpha-tocopherol. Potential utilization of the method includes monitoring of drug concentrations in patients treated with retinoic acid for acute promyelocytic leukemia or for other malignancies in clinical trials.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/NR9096" target="_blank" >NR9096: Risc factors of atherosclerosis in cancer patients</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Separation Science

  • ISSN

    1615-9306

  • e-ISSN

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

    15-16

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    8

  • Pages from-to

    2804-2811

  • UT code for WoS article

    000269413400038

  • EID of the result in the Scopus database