Analysis of D1853N ATM polymorphism in radiosensitive patients with cervical carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F11%3A10105261" target="_blank" >RIV/00179906:_____/11:10105261 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/11:10105261
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Analysis of D1853N ATM polymorphism in radiosensitive patients with cervical carcinoma
Original language description
The aims of our study were: (i) to find and validate a method for fast and reliable analysis of the D1853N (5557G}A) genetic polymorphism in the ATM (ataxia-telangiectasia mutated) gene; ii) to target mutagenesis to ATM exon 39 to receive control samplescontaining the 5557A allele in homozygous state; and (iii) to analyse a group of patients suffering from cervical carcinoma with adverse responses to radiotherapy. The 5557A variant was found in three of twenty women (16 %). Our data show that the prevalence of the 5557A allelic variant in cervical cancer subjects with adverse responses after irradiation does not differ from the prevalence common in Caucasians.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11334" target="_blank" >NT11334: Genetic prediction of late toxicity of radiotherapy for cervical cancer</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Kralove
ISSN
1211-4286
e-ISSN
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Volume of the periodical
54
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
111-116
UT code for WoS article
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EID of the result in the Scopus database
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