Pneumocystis pneumonia during medicamentous treatment of Cushing's syndrome - a description of two cases

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F11%3A10105266" target="_blank" >RIV/00179906:_____/11:10105266 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/11:10105266

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Pneumocystis pneumonia during medicamentous treatment of Cushing's syndrome - a description of two cases

Original language description

Only a few cases of pneumocystis pneumonia (PCP) in Cushing's syndrome have been published in the literature so far. In the majority of these patients, the pneumonia occurred after reduction of the hypercortisolism with medicamentous treatment. We reporttwo cases of PCP during conservative treatment of hypercortisolism. We describe clinical, imaging and laboratory findings in two patients and review published cases of pneumocystits pneumonia in Cushing''s syndrome. A 60-year-old woman and 20-year-old man with Cushing''s syndrome due to ectopic ACTH syndrome were treated at our department. Both developed pneumocystis pneumonia early after treatment with ketoconazole and ethomidate bromide had been introduced and the levels of cortisol rapidly decreased. PCP prophylaxis in patients with high cortisolemia should be started before treatment of hypercortisolism in current practice. Gradual lowering of plasma cortisol should also reduce the risk of infection by Pneumocystis jiroveci.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

<a href="/en/project/NT11344" target="_blank" >NT11344: Quantitative analysis of somatostatin receptors in pituitary adenomas.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Kralove

ISSN

1211-4286

e-ISSN

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Volume of the periodical

54

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

127-130

UT code for WoS article

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EID of the result in the Scopus database

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