Isolated thoracic aortitis: clinicopathological and immunohistochemical study of 11 cases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F11%3A10106038" target="_blank" >RIV/00179906:_____/11:10106038 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/11:10106038
Result on the web
<a href="http://www.ncbi.nlm.nih.gov/pubmed/21036629" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/21036629</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carpath.2010.09.003" target="_blank" >10.1016/j.carpath.2010.09.003</a>
Alternative languages
Result language
angličtina
Original language name
Isolated thoracic aortitis: clinicopathological and immunohistochemical study of 11 cases
Original language description
Isolated thoracic aortitis (ITA) is diagnosed in a variable proportion of patients operated on for dilation/aneurysm of ascending aorta. The etiopathogenesis of ITA remains unclear. We studied 11 cases of ITA in order to determine the role of IgG4-mediated immune responses in its pathogenesis. The series included 9 females and 2 males aged 52-79 years. All patients developed aortic incompetence due to dilation/aneurysm of ascending aorta. None of the patients had a history of IgG4-related disease neither did they develop features of such disease during the follow-up period. The microscopic findings included the presence of lymphoplasmacellular fibrosing infiltrate of varied intensity involving the adventitia and media of aorta. This inflammation was associated with severe medial elastic fiber defects. Obliterative phlebitis of the vasa vasorum was absent. Immunohistochemically, the inflammatory infiltrate comprised T- and B-lymphocytes as well as plasma cells. The plasma cell populatio
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cardiovascular Pathology
ISSN
1054-8807
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
6
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
352-360
UT code for WoS article
000296404500004
EID of the result in the Scopus database
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