Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F11%3A10133757" target="_blank" >RIV/00179906:_____/11:10133757 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/11:10133757
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2362.2010.02431.x/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2362.2010.02431.x/pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1365-2362.2010.02431.x" target="_blank" >10.1111/j.1365-2362.2010.02431.x</a>
Alternative languages
Result language
angličtina
Original language name
Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions
Original language description
Despite the importance of myocardial vasculature in many pathological conditions, little information is available about cardiac and coronary lymphatic vessels in normal and pathological conditions. Materials and methods: Vasculature was assessed by immunohistochemistry with CD 31 and lymphatic endothelium with markers podoplanin and LYVE-1 in 16 children and 20 adult autopsy hearts. Valve biopsies were collected from eight adults. Results: The highest number of lymphatics was found in valves in infective endocarditis, where they accounted nearly 100% of all vessels in certain areas. An increased number of lymphatics was also found in degenerative calcified stenosis, whereas the number was reduced in myxoid degeneration. Lymphatics grew in areas rich inextracellular matrix, whereas inflammatory cell-rich areas were more prone to angiogenesis. Progressive atherosclerotic lesions rich in calcium and cholesterol crystals revealed increased lymphangiogenesis in media. The highest number of
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Clinical Investigation
ISSN
0014-2972
e-ISSN
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Volume of the periodical
41
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
487-497
UT code for WoS article
000289253600004
EID of the result in the Scopus database
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