Confirmatory testing in primary aldosteronism: extensive medication switching is not needed in all patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10125031" target="_blank" >RIV/00179906:_____/12:10125031 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/12:10125031

Result on the web

<a href="http://dx.doi.org/10.1530/EJE-11-0914" target="_blank" >http://dx.doi.org/10.1530/EJE-11-0914</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1530/EJE-11-0914" target="_blank" >10.1530/EJE-11-0914</a>

Result language

angličtina

Original language name

Confirmatory testing in primary aldosteronism: extensive medication switching is not needed in all patients

Original language description

Objective: Confirmatory testing of suspected primary aldosteronism (PA) requires an extensive medication switch that can be difficult for patients with severe complicated hypertension and/or refractory hypokalemia. For this reason, we investigated the effect of chronic antihypertensive medication on confirmatory testing results. To allow the results to be interpreted, the reproducibility of confirmatory testing was also evaluated. Design and methods: The study enrolled 114 individuals with suspected PAwho underwent two confirmatory tests. The patients were divided into two groups. In Group A, both tests were performed on the guidelines-recommended therapy, i.e. not interfering with the renin-angiotensin-aldosterone system. In Group B, the first test was performed on chronic therapy with the exclusion of thiazides, loop diuretics, and aldosterone antagonists; and the second test was performed on guidelines-recommended therapy. Saline infusion, preceded by oral sodium loading, was used

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Endocrinology

ISSN

0804-4643

e-ISSN

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Volume of the periodical

166

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

679-686

UT code for WoS article

000302343500014

EID of the result in the Scopus database

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