Risk of venous thromboembolism during treatment with antipsychotic agents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10126128" target="_blank" >RIV/00179906:_____/12:10126128 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/12:10126128
Result on the web
<a href="http://dx.doi.org/10.1111/pcn.12001" target="_blank" >http://dx.doi.org/10.1111/pcn.12001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/pcn.12001" target="_blank" >10.1111/pcn.12001</a>
Alternative languages
Result language
angličtina
Original language name
Risk of venous thromboembolism during treatment with antipsychotic agents
Original language description
The evidence to date on the relation between the risk of venous thromboembolic disease (VTE) and antipsychotic agents derives primarily from observational and case history studies. While an increased risk of VTE has been associated with first-generationlow-potency antipsychotic agents, particularly clozapine, there appears to be a growing number of reports on the occurrence of this adverse reaction during the use of second-generation antipsychotics, such as risperidone and olanzapine. The highest riskof pathological blood clotting emerges during the first 3 months after initiation of treatment with the product. Potential etiopathogenetic factors leading to VTE during treatment with antipsychotic agents include sedation, obesity, elevation of antiphospholipid antibodies, increased platelet activation and aggregation, hyperhomocysteinemia, and hyperprolactinemia. Diagnoses of schizophrenia and/or bipolar affective disorder, as well as hospitalization or stress with sympathetic activati
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Psychiatry and Clinical Neurosciences
ISSN
1323-1316
e-ISSN
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Volume of the periodical
66
Issue of the periodical within the volume
7
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
541-552
UT code for WoS article
000312649000001
EID of the result in the Scopus database
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