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Risk of venous thromboembolism during treatment with antipsychotic agents

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10126128" target="_blank" >RIV/00179906:_____/12:10126128 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/12:10126128

  • Result on the web

    <a href="http://dx.doi.org/10.1111/pcn.12001" target="_blank" >http://dx.doi.org/10.1111/pcn.12001</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/pcn.12001" target="_blank" >10.1111/pcn.12001</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Risk of venous thromboembolism during treatment with antipsychotic agents

  • Original language description

    The evidence to date on the relation between the risk of venous thromboembolic disease (VTE) and antipsychotic agents derives primarily from observational and case history studies. While an increased risk of VTE has been associated with first-generationlow-potency antipsychotic agents, particularly clozapine, there appears to be a growing number of reports on the occurrence of this adverse reaction during the use of second-generation antipsychotics, such as risperidone and olanzapine. The highest riskof pathological blood clotting emerges during the first 3 months after initiation of treatment with the product. Potential etiopathogenetic factors leading to VTE during treatment with antipsychotic agents include sedation, obesity, elevation of antiphospholipid antibodies, increased platelet activation and aggregation, hyperhomocysteinemia, and hyperprolactinemia. Diagnoses of schizophrenia and/or bipolar affective disorder, as well as hospitalization or stress with sympathetic activati

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FL - Psychiatry, sexology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Psychiatry and Clinical Neurosciences

  • ISSN

    1323-1316

  • e-ISSN

  • Volume of the periodical

    66

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    12

  • Pages from-to

    541-552

  • UT code for WoS article

    000312649000001

  • EID of the result in the Scopus database