TLR2 in pleural fluid is modulated by talc particles during pleurodesis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10126162" target="_blank" >RIV/00179906:_____/12:10126162 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/12:10126162

Result on the web

<a href="http://www.hindawi.com/journals/cdi/2012/158287/" target="_blank" >http://www.hindawi.com/journals/cdi/2012/158287/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2012/158287" target="_blank" >10.1155/2012/158287</a>

Result language

angličtina

Original language name

TLR2 in pleural fluid is modulated by talc particles during pleurodesis

Original language description

The aim of this study was to examine the role of TLR2 molecule in pleural space during thoracoscopic talc pleurodesis period in patients with malignant pleural effusion. We analyzed TLR2 molecule in soluble form as well as on membrane of granulocytes inpleural fluid. Pleural fluid examination was done at three intervals during pleurodesis procedure: 1st - before the thoracoscopic procedure, 2nd - 2 hours after the terminating thoracoscopic procedure with talc insufflation, 3rd - 24 hours after the thoracoscopic procedure. We reported significant increase of soluble TLR2 molecule in pleural fluid effusion during talc pleurodesis from preoperative value. This increase was approximately 8-fould in the interval of 24 hours. The changes on granulocyte population were quite different. The mean fluorescent intensity of membrane TLR2 molecule examined by flow cytometry on granulocyte population significantly decreased after talc exposure with comparison to prethoracoscopic density. To estimat

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical and Developmental Immunology

ISSN

1740-2522

e-ISSN

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Volume of the periodical

2012

Issue of the periodical within the volume

December

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

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UT code for WoS article

000312794800001

EID of the result in the Scopus database

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