The decrease of mean platelet volume after extracorporeal LDL-cholesterol elimination

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F13%3A10133853" target="_blank" >RIV/00179906:_____/13:10133853 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/13:10133853

Result on the web

<a href="http://dx.doi.org/10.1016/j.atherosclerosissup.2012.10.019" target="_blank" >http://dx.doi.org/10.1016/j.atherosclerosissup.2012.10.019</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.atherosclerosissup.2012.10.019" target="_blank" >10.1016/j.atherosclerosissup.2012.10.019</a>

Result language

angličtina

Original language name

The decrease of mean platelet volume after extracorporeal LDL-cholesterol elimination

Original language description

Objective: Mean platelet volume is arousing increasing interest as a new independent cardiovascular risk factor. Large platelets are likely to be more reactive. If mean platelet volume would drop after LDL-lowering therapy, decreased MPV could be one ofthe markers of successful therapy. Therefore, we investigated mean platelet volume after extracorporeal LDL-cholesterol elimination. Methods: Mean platelet volume was investigated in patients with severe familial hypercholesterolemia long-term treated (3-12 years) by LDL-apheresis (immunoapheresis) or cascade filtration. Plasma was obtained by centrifugation. Adsorbers Lipopak 400 were used for immunoapheresis and filters Evaflux 4A were used for cascade filtration. 95 pair samples were measured (beforeand after the procedures) in a group of 12 patients - each patient 8 times in 4 years. Results: Mean platelet volume before the procedures was 10.891 fl, CI 10.25-11.53. Mean platelet volume after the procedures decreased - 10.478 fl, CI

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/NT12287" target="_blank" >NT12287: The role of insulin resistance in the pathogenesis of cardiometabolic risk in diabetes mellitus</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Atherosclerosis Supplements

ISSN

1567-5688

e-ISSN

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Volume of the periodical

14

Issue of the periodical within the volume

1

Country of publishing house

IE - IRELAND

Number of pages

5

Pages from-to

77-81

UT code for WoS article

000314885000014

EID of the result in the Scopus database

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