Antithrombotic therapy in patients after valve surgery with special attention to the combination of anticoagulant and antiplatelet therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F13%3A10189286" target="_blank" >RIV/00179906:_____/13:10189286 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/13:10189286

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0010865013000118#" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0010865013000118#</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.crvasa.2013.01.009" target="_blank" >10.1016/j.crvasa.2013.01.009</a>

Result language

angličtina

Original language name

Antithrombotic therapy in patients after valve surgery with special attention to the combination of anticoagulant and antiplatelet therapy

Original language description

Patients after implantation of mechanical valves need life-long anticoagulant therapy. Nearly 30% of these patients have also indication for antiplatelet therapy because of concomitant ischemic heart disease or peripheral arterial disease. Combined anticoagulant and dual antiplatelet therapy (so called triple therapy - aspirin, clopidogrel and vitamin K antagonists) is indicated in patients with acute coronary syndrome and after percutaneous coronary intervention (PCI) for a different time according tothe type of stent used during the procedure. Triple therapy is substantially more efficacious in reducing the occurrence of cardiovascular events and mortality in patients undergoing PCI with an indication for long-term anticoagulant therapy, compared with dual antiplatelet therapy. On the other hand it carries 3.5 to 4 times higher risk of bleeding in treated patients. Recently new anticoagulants (dabigatran, rivaroxaban, apixaban) and antiplatelet drugs (prasugrel and ticagrelor) came

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cor et Vasa

ISSN

0010-8650

e-ISSN

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Volume of the periodical

55

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

"e164"-"e169"

UT code for WoS article

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EID of the result in the Scopus database

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