Immunogenicity and safety of an investigational multicomponent, recombinant, meningococcal serogroup B vaccine (4CMenB) administered concomitantly with routine infant and child vaccinations: results of two randomised trials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F13%3A10191900" target="_blank" >RIV/00179906:_____/13:10191900 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/S0140-6736(12)61961-8" target="_blank" >http://dx.doi.org/10.1016/S0140-6736(12)61961-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/S0140-6736(12)61961-8" target="_blank" >10.1016/S0140-6736(12)61961-8</a>

Result language

angličtina

Original language name

Immunogenicity and safety of an investigational multicomponent, recombinant, meningococcal serogroup B vaccine (4CMenB) administered concomitantly with routine infant and child vaccinations: results of two randomised trials

Original language description

We estimate and describe the incidence rates, mortality, and cost of CAP (community-acquired pneumonia), in both inpatient and outpatient settings, in the Czech Republic (CZ), Slovakia (SK), Poland (PL), and Hungary (HU). A retrospective analysis was conducted on administrative data from the health ministry and insurance reimbursement claims with a primary diagnosis of pneumonia in 2009 to determine hospitalization rates, costs, and mortality in adults }= 50 years of age. Patient chart reviews were conducted to estimate the number of outpatient cases. Among all adults }= 50 years, the incidence of hospitalized CAP per 100,000 person years was: 456.6 (CZ), 504.6 (SK), 363.9 (PL), and 845.3 (HU). The average fatality rate for all adults }= 50 is 19.1%, and for each country; 21.7% (CZ), 20.9% (SK), 18.6% (PL), 17.8% (HU). Incidence, fatality, and likelihood of hospitalization increased with advancing age. Total healthcare costs of CAP in EUR was 12,579,543 (CZ); 9,160,774 (SK); 22,409,085

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Lancet

ISSN

0140-6736

e-ISSN

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Volume of the periodical

381

Issue of the periodical within the volume

9869

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

825-835

UT code for WoS article

000316060600032

EID of the result in the Scopus database

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