The Role of Protein p16(INK4a) in Glottic Laryngeal Squamous Cell Carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10281758" target="_blank" >RIV/00179906:_____/14:10281758 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/14:10281758 RIV/00216208:11150/14:10281758
Result on the web
<a href="http://download.springer.com/static/pdf/794/art%253A10.1007%252Fs12253-014-9773-y.pdf?auth66=1416393279_47d52c012a468b306ad30b2aaac4dc59&ext=.pdf" target="_blank" >http://download.springer.com/static/pdf/794/art%253A10.1007%252Fs12253-014-9773-y.pdf?auth66=1416393279_47d52c012a468b306ad30b2aaac4dc59&ext=.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12253-014-9773-y" target="_blank" >10.1007/s12253-014-9773-y</a>
Alternative languages
Result language
angličtina
Original language name
The Role of Protein p16(INK4a) in Glottic Laryngeal Squamous Cell Carcinoma
Original language description
Head and neck squamous cell cancer (HNSCC) includes tumors of various anatomical sites sharing the common etiological factors. However some differences in pathogenesis and prognosis of HNSCC have been hitherto documented. Laryngeal squamous cell carcinoma (LSCC) is one the most common type of the head and neck cancer. The majority of laryngeal cancers are located in the glottic area. P16 was recently documented to be important prognostic marker in many tumors including HNSCC. The aim of our study was toassess the significance of p16 expression in glottic LSCC. Fifty eight patients after surgical treatment of the glottic LSCC were enrolled in the retrospective study. The p16 expression was immunohistochemically detected and semiquantitatively evaluatedin tumor tissue. The results were statistically correlated with clinical and pathological parameters. Protein p16 was expressed in glottic LSCC of 15 patients (25.9 %). Statistically significant higher p16 overexpression was proven in no
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pathology Oncology Research
ISSN
1219-4956
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
4
Country of publishing house
HU - HUNGARY
Number of pages
7
Pages from-to
909-915
UT code for WoS article
000342554600019
EID of the result in the Scopus database
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