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D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10282892" target="_blank" >RIV/00179906:_____/14:10282892 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11150/14:10282892

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.thromres.2013.12.044" target="_blank" >http://dx.doi.org/10.1016/j.thromres.2013.12.044</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.thromres.2013.12.044" target="_blank" >10.1016/j.thromres.2013.12.044</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer

  • Original language description

    Background: The prognostic value of D-dimer testing in patients with acute pulmonary embolism (PE) has not been thoroughly studied. Methods: We used the RIETE Registry data to assess the 90-day prognostic value of increased IL Test D-dimer (R) levels atbaseline in patients with PE, according to the presence or absence of cancer. Results: As of May 2013, 3,283 patients with acute PE underwent D-dimer testing using IL Test D-dimer (R). Among 2,588 patients without cancer, those with D-dimer levels in thehighest quartile had a higher rate of fatal PE (2.6% vs. 0.9%; p = 0.002), fatal bleeding (1.1% vs. 0.3%; p = 0.017) and all-cause death (9.1% vs. 4.4%; p < 0.001) at 90 days compared with those with levels in the lowest quartiles. Among 695 patients with cancer, those with levels in the highest quartile had a similar rate of fatal PE or fatal bleeding but higher mortality (35% vs. 24%; p < 0.01). On multivariate analysis, non-cancer patients with D-dimer levels in the highest quartile

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Thrombosis Research

  • ISSN

    0049-3848

  • e-ISSN

  • Volume of the periodical

    133

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    384-389

  • UT code for WoS article

    000331540400016

  • EID of the result in the Scopus database