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Multipotent mesenchymal stromal cells in otorhinolaryngology

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10283783" target="_blank" >RIV/00179906:_____/14:10283783 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/14:00432940 RIV/00216208:11150/14:10283783

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S0306987714001352" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0306987714001352</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.mehy.2014.03.022" target="_blank" >10.1016/j.mehy.2014.03.022</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Multipotent mesenchymal stromal cells in otorhinolaryngology

  • Original language description

    Multipotent mesenchymal stromal cells (MSCs) are primitive cells capable of restoring damaged mesenchyme and with the ability to differentiate into mature cells of bone, cartilage, muscle, fat, nerve or fibrous tissues. MSCs are therefore good candidatesfor applications in regenerative medicine and cell based therapy. They regenerate through self-renewal, differentiational capacity, immune modulation and secretion of bioactive molecules. Authors present a review of MSCs applications in otorhinolaryngology. The major interest is focused on phonosurgery, sensorineural deafness and reconstruction of large tissue defects with bone, cartilage or soft tissue replacement. Current evidence of MSCs treatment efficacy in otorhinolaryngology is based on animal models. The true impact on clinical treatment will not be known until clinical studies prove functional outcomes in human medicine.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medical Hypotheses

  • ISSN

    0306-9877

  • e-ISSN

  • Volume of the periodical

    82

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    5

  • Pages from-to

    769-773

  • UT code for WoS article

    000336704200028

  • EID of the result in the Scopus database