Lipoprotein-associated phospholipase A2 mass level is increased in elderly subjects with type 2 diabetes mellitus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10283845" target="_blank" >RIV/00179906:_____/14:10283845 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/14:10283845
Result on the web
<a href="http://dx.doi.org/10.1155/2014/278063" target="_blank" >http://dx.doi.org/10.1155/2014/278063</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2014/278063" target="_blank" >10.1155/2014/278063</a>
Alternative languages
Result language
angličtina
Original language name
Lipoprotein-associated phospholipase A2 mass level is increased in elderly subjects with type 2 diabetes mellitus
Original language description
Objective. Lipoprotein-associated phospholipase A2 (Lp-PLA 2) is extensively expressed by advanced atherosclerotic lesions and may play a role in plaque instability. We selected a group of elderly subjects that underwent transcatheter aortic valve implantation (TAVI) or balloon angioplasty (BA) and separated them into two groups, diabetic and nondiabetic, to compare the level of Lp-PLA2 mass between them. Methods. 44 patients aged 79.6 +- 5.6 years with symptomatic severe aortic valve stenosis underwentTAVI (n = 35) or BA (n = 9). 21 subjects had confirmed type 2 diabetes mellitus. Lp-PLA2 mass was measured using an enzyme-linked immunosorbent assay kit (USCN Life Science, China) before and 3 days after the procedure. Results. Lp-PLA2 mass was significantly elevated in this population (1296 +- 358 ng/mL before TAVI; 1413 +- 268 ng/mL before BA) and further increased after TAVI (1604 +- 437 ng/mL, P < 0. 01) or BA (1808 +- 303 ng/mL, P < 0. 01). Lp-PLA2 mass was significantly increased
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT12287" target="_blank" >NT12287: The role of insulin resistance in the pathogenesis of cardiometabolic risk in diabetes mellitus</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Diabetes Research
ISSN
2314-6745
e-ISSN
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Volume of the periodical
2014
Issue of the periodical within the volume
10 April
Country of publishing house
EG - EGYPT
Number of pages
6
Pages from-to
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UT code for WoS article
000334777800001
EID of the result in the Scopus database
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