Bedside assessment of amniotic fluid interleukin-6 in preterm prelabor rupture of membranes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10283857" target="_blank" >RIV/00179906:_____/14:10283857 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/14:10283857 RIV/00216275:25520/14:39898518
Result on the web
<a href="http://dx.doi.org/10.1016/j.ajog.2014.03.069" target="_blank" >http://dx.doi.org/10.1016/j.ajog.2014.03.069</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ajog.2014.03.069" target="_blank" >10.1016/j.ajog.2014.03.069</a>

Result language
angličtina
Original language name
Bedside assessment of amniotic fluid interleukin-6 in preterm prelabor rupture of membranes
Original language description
OBJECTIVE: The objective of the study was to determine the diagnostic indices and predictive values by bedside assessment of amniotic fluid interleukin-6 (IL-6) concentration in the identification of microbial invasion of the amniotic cavity (MIAC) and/or histological chorioamnionitis (HCA) in patients with preterm prelabor rupture of membranes. STUDY DESIGN: One hundred twenty-four women with singleton pregnancies were included in this study. The amniotic fluid was sampled by transabdominal amniocentesis at the time of admission. IL-6 concentrations were assessed with an immunoassay. RESULTS: The presence of MIAC, HCA, or the coexistence of both was associated with higher amniotic fluid concentrations of IL-6 in both a crude and adjusted analysis. Theamniotic fluid concentration of IL-6 of 1000 pg/mL was determined to be the best cutoff value for the prediction of MIAC (sensitivity of 50%, specificity of 95%, positive predictive value of 82%, negative predictive value of 81%, and lik
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Project
<a href="/en/project/NT13461" target="_blank" >NT13461: The relationship between bacterial load in amniotic fluid and the intensity of intraamniotic inflammatory response in women with preterm prelabor rupture of membranes</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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