Diagnostic and Predictive Value of Ultrasound and Isotope Thyroid Scanning, Alone and in Combination, in Infants Referred with Thyroid-Stimulating Hormone Elevation on Newborn Screening

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10286175" target="_blank" >RIV/00179906:_____/14:10286175 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.jpeds.2013.11.057" target="_blank" >http://dx.doi.org/10.1016/j.jpeds.2013.11.057</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jpeds.2013.11.057" target="_blank" >10.1016/j.jpeds.2013.11.057</a>

Result language

angličtina

Original language name

Diagnostic and Predictive Value of Ultrasound and Isotope Thyroid Scanning, Alone and in Combination, in Infants Referred with Thyroid-Stimulating Hormone Elevation on Newborn Screening

Original language description

Objective To determine the diagnostic and predictive value of ultrasound and radioisotope scans of the thyroid, alone and in combination, during a single visit after initial referral by the screening laboratory with thyroid-stimulating hormone (TSH) elevation. Study design Retrospective blind review of ultrasound and radioisotope images followed by final diagnosis based on clinical features, biochemistry, imaging, and molecular genetic study. Results Infants (n = 97; 61 female) with median birthweight 3.38 kg (range 2.04-4.86) and gestation 40 weeks (range 33-42), underwent successful dual thyroid ultrasound and technetium-99m pertechnetate radioisotope scan in a single center. Combined scanning at the initial visit resulted in a correct final diagnosis in 79 of 97 (81%) cases. One patient was misdiagnosed initially as having athyreosis as the result of delayed radioisotope scan and the diagnosis of ectopia made later on diagnostic challenge. The specificity/sensitivity for radioisotop

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FG - Paediatrics

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Pediatrics

ISSN

0022-3476

e-ISSN

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Volume of the periodical

164

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

846-854

UT code for WoS article

000333258900037

EID of the result in the Scopus database

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