Cessation of Nocturnal Enuresis After Intervention with Methylcobalamin in an 18-Year-Old Patient with Autism

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F15%3A10297439" target="_blank" >RIV/00179906:_____/15:10297439 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1089/cap.2014.0023" target="_blank" >http://dx.doi.org/10.1089/cap.2014.0023</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1089/cap.2014.0023" target="_blank" >10.1089/cap.2014.0023</a>

Result language

angličtina

Original language name

Cessation of Nocturnal Enuresis After Intervention with Methylcobalamin in an 18-Year-Old Patient with Autism

Original language description

Nocturnal enuresis, incontinence in discrete episodes while asleep, is one of the most common disorders among children (Neve us et al. 2006). It is a multifactorial disorder. Several risk factors have been described so far, including developmental delay, as well as genetic and psychosocial factors (Butler 2004; Caldwell et al. 2005). Clinical categorization distinguishes monosymptomatic enuresis, which is usually linked to the abnormal nocturnal vasopressin release or polyuria, and non-monosymptomatic enuresis caused by bladder dysfunction or overactivity (Butler 2004; Deshpande and Caldwell 2012; Naseri and Hiradfar 2012). Children with developmental delay and other neurological disorders often develop nocturnal enuresis ( Jarvelin 1989; Simonoff et al. 2008; Zhao et al. 2009; Gor et al. 2012; Nappo 2012). The treatment of enuresis in these patients is more difficult because of psychological and behavioral changes. Pharmacological intervention using desmopressin and anticholinergic drugs is questionable, because of the mixed outcomes from the treatment (Naitoh et al. 2005; Yucel et al. 2011; Gor et al. 2012), as well as severe side effects ( Muller et al. 2004; Gish et al. 2009; Friedman et al. 2011). Here, we report a case of disappearance of nocturnal enuresis in an 18-year-old patient with childhood autism after oral application of a low dose of methylcobalamin. The patient was enrolled in the study to examine the effect of methylcobalamin on the psycho- behavioral profile in patients with autism.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Child and Adolescent Psychopharmacology

ISSN

1044-5463

e-ISSN

—

Volume of the periodical

25

Issue of the periodical within the volume

10

Country of publishing house

US - UNITED STATES

Number of pages

3

Pages from-to

821-823

UT code for WoS article

000366723900012

EID of the result in the Scopus database

2-s2.0-84951286699