Computed tomography pulmonary embolism residua index (CTPER-index): a simple tool for pulmonary embolism residua description

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10326881" target="_blank" >RIV/00179906:_____/16:10326881 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/16:10326881

Result on the web

<a href="http://dx.doi.org/10.5152/akd.2015.6178" target="_blank" >http://dx.doi.org/10.5152/akd.2015.6178</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5152/akd.2015.6178" target="_blank" >10.5152/akd.2015.6178</a>

Result language

angličtina

Original language name

Computed tomography pulmonary embolism residua index (CTPER-index): a simple tool for pulmonary embolism residua description

Original language description

Objective: Chronic thromboembolic pulmonary hypertension (CTEPH) is a relatively common long-term complication of acute pulmonary embolism (PE) with severely negative impact on the patient's quality of life and prognosis. The aim of our study was to assess morphological changes, with respect to CTEPH development, in the pulmonary artery vascular bed 6 months after diagnosis of acute PE as the first thromboembolic event in the patient' s history. Methods: Our prospective study included a population of 87 consecutive patients with proven PE. Multidetector computer tomography pulmonary arteriography (CTA) was performed 6 months after acute PE to assess residua of thrombi and abnormalities supporting the presence of pulmonary hypertension. To quantify the individual totality of morphological abnormalities, a computer tomography pulmonary embolism residua index (CTPER-index) was constructed and groups of patients with and without CTEPH were compared. The study follow-up was 24 months, with echocardiography performed 6, 12, and 24 months after PE. Results: Morphological abnormalities corresponding to thrombi residua or pulmonary hypertension on CTA were found in 68% of patients. The CTPER-index reached significantly higher values in patients with CTEPH during a 2-year follow-up. A CTPER-index value >= 4 equates to a 12-fold higher risk of CTEPH development (p=0.013) with sensitivity 0.80 (95% CI 0.31; 0.989) and specificity 0.79 (95% CI 0.754; 0.799). Conclusion: Our CTPER-index may provide useful information for a clinician performing CTA for differential diagnosis of dyspnea in a patient with a history of PE.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anatolian Journal of Cardiology

ISSN

2149-2263

e-ISSN

—

Volume of the periodical

16

Issue of the periodical within the volume

4

Country of publishing house

TR - TURKEY

Number of pages

6

Pages from-to

270-275

UT code for WoS article

000377194000009

EID of the result in the Scopus database

2-s2.0-84994275744