Microsatellite instability in melanoma: a comprehensive review

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10330206" target="_blank" >RIV/00179906:_____/16:10330206 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/16:10330206
Result on the web
<a href="http://dx.doi.org/10.1097/CMR.0000000000000298" target="_blank" >http://dx.doi.org/10.1097/CMR.0000000000000298</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/CMR.0000000000000298" target="_blank" >10.1097/CMR.0000000000000298</a>

Result language
angličtina
Original language name
Microsatellite instability in melanoma: a comprehensive review
Original language description
Microsatellite instability (MS) and mismatch repair deficiency are an emerging issue in oncology and molecular pathology. Besides being associated with better clinical outcome in colon cancer, MSI also harbors the potential to predict response to chemotherapy and immunotherapy. MSI was also observed in other solid tumors, including endometrial cancer, ovarian cancer, and melanoma, besides colon cancer. Strong evidence shows that MSI is a frequent event in melanoma. However, the data on MSI prevalence, pathogenesis, and clinical consequences in melanoma are limited. Therefore, we summarize the current knowledge on MSI in melanoma and outline future perspectives and clinical implications, including its role as a prognostic and /or a predictive factor.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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