Cutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10331063" target="_blank" >RIV/00179906:_____/16:10331063 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/16:10331063 RIV/61989592:15110/16:33159410

Result on the web

<a href="http://dx.doi.org/10.3109/10428194.2015.1128542" target="_blank" >http://dx.doi.org/10.3109/10428194.2015.1128542</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/10428194.2015.1128542" target="_blank" >10.3109/10428194.2015.1128542</a>

Result language

angličtina

Original language name

Cutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients

Original language description

Skin infiltration in multiple myeloma (skin MM) is a rare clinical problem. Only a few cases of skin involvement have been reported, primarily in single case reports. We analyzed and present the clinical outcomes, immunohistochemistry and cytogenetic features, and relevant laboratory data on 53 biopsy-proven skin MM cases. The median time from MM diagnosis to skin involvement was 2 years. There appears to be an overrepresentation of immunoglobulin class A (IgA) and light chain disease in skin MM. We found no correlation between CD56 negative MM and skin infiltration. We found that skin MM patients presented in all MM stages (i.e. ISS stages I to III), and there was no preferential cytogenetic abnormality. Patients with skin MM carry a very poor prognosis with a median overall survival (OS) of 8.5 months as time from skin involvement. Moreover, patients with IgA disease and plasmablastic morphology appear to have a worse OS.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Leukemia &amp; Lymphoma

ISSN

1042-8194

e-ISSN

—

Volume of the periodical

57

Issue of the periodical within the volume

9

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

2071-2076

UT code for WoS article

000381372800011

EID of the result in the Scopus database

2-s2.0-84953264965