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Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction A Randomized Clinical Trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10331962" target="_blank" >RIV/00179906:_____/16:10331962 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/16:00090655 RIV/65269705:_____/16:00065473 RIV/00064173:_____/16:N0000082 RIV/00843989:_____/16:E0106090

  • Result on the web

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=XH9LT7ynNL" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=XH9LT7ynNL</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1001/jama.2016.3609" target="_blank" >10.1001/jama.2016.3609</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction A Randomized Clinical Trial

  • Original language description

    IMPORTANCE p38 Mitogen-activated protein kinase (MAPK)-stimulated inflammation is implicated in atherogenesis, plaque destabilization, and maladaptive processes in myocardial infarction (MI). Pilot data in a phase 2 trial in non-ST elevation MI indicated that the p38 MAPK inhibitor losmapimod attenuates inflammation and may improve outcomes.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30201 - Cardiac and Cardiovascular systems

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    JAMA: The Journal of the American Medical Association

  • ISSN

    0098-7484

  • e-ISSN

  • Volume of the periodical

    315

  • Issue of the periodical within the volume

    15

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    1591-1599

  • UT code for WoS article

    000374289300019

  • EID of the result in the Scopus database

    2-s2.0-84964330151