Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10332814" target="_blank" >RIV/00179906:_____/16:10332814 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/16:10332814
Result on the web
<a href="http://dx.doi.org/10.1093/molehr/gav074" target="_blank" >http://dx.doi.org/10.1093/molehr/gav074</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/molehr/gav074" target="_blank" >10.1093/molehr/gav074</a>
Alternative languages
Result language
angličtina
Original language name
Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes
Original language description
STUDY HYPOTHESIS: In women with preterm premature rupture of the membranes (PPROM), increased oxidative stress may accelerate premature cellular senescence, senescence-associated inflammation and proteolysis, which may predispose them to rupture. STUDY FINDING: We demonstrate mechanistic differences between preterm birth (PTB) and PPROM by revealing differences in fetal membrane redox status, oxidative stress-induced damage, distinct signaling pathways and senescence activation.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Human Reproduction
ISSN
1360-9947
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
143-157
UT code for WoS article
000371183800007
EID of the result in the Scopus database
2-s2.0-84961588998