Fast determination of omeprazole in extemporaneous suspensions used in paediatrics and stability studies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F19%3A10398665" target="_blank" >RIV/00179906:_____/19:10398665 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11160/19:10398665
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=g9CxFq0L6Y" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=g9CxFq0L6Y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c8ay02547a" target="_blank" >10.1039/c8ay02547a</a>
Alternative languages
Result language
angličtina
Original language name
Fast determination of omeprazole in extemporaneous suspensions used in paediatrics and stability studies
Original language description
A simple and fast ultra-high-performance liquid chromatography method with UV detection for the separation and quantification of omeprazole and the impurities of omeprazole and methylparaben (the internal standard) in six extemporaneous suspensions has been developed and fully validated. Isocratic elution was carried out using a Kinetex(TM) C18 column, 50 x 2.1 mm packed with 1.7 mu m porous shell particles, and the mobile phase comprised a mixture of phosphate buffer and acetonitrile. The separation of all compounds was achieved within 2 min. This method was successfully applied for stability evaluation of the developed formulations, which are now being used in the therapy of acid-related disorders in paediatric patients.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/EF15_003%2F0000465" target="_blank" >EF15_003/0000465: Establishment of Specialized Team for Advanced Research on Separation Science</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Analytical Methods
ISSN
1759-9660
e-ISSN
—
Volume of the periodical
11
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
517-523
UT code for WoS article
000457360700011
EID of the result in the Scopus database
2-s2.0-85060648516