Surgical Pleth Index And Analgesia Nociception Index for intraoperative analgesia in patients undergoing neurosurgical spinal procedures, a comparative randomized study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F19%3A10398843" target="_blank" >RIV/00179906:_____/19:10398843 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/19:10398843
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hkC0-UUPa8" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=hkC0-UUPa8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.23736/S0375-9393.19.13765-0" target="_blank" >10.23736/S0375-9393.19.13765-0</a>
Alternative languages
Result language
angličtina
Original language name
Surgical Pleth Index And Analgesia Nociception Index for intraoperative analgesia in patients undergoing neurosurgical spinal procedures, a comparative randomized study
Original language description
BACKGROUND: The Surgical Plethysmographic Index (SPI) and the Analgesia Nociception Index (ANI) have been suggested for the non-invasive intraoperative monitoring of nociception/anti-nociception balance. We aimed to compare patterns of intraoperative use of opioids, postoperative cortisol levels and postoperative pain scores after intraoperative analgesia guided either by ANI, SPI or anaesthesiologist's judgment. MATERIAL AND METHODS: Seventy two adult ASA I - III patients scheduled for elective neurosurgical spinal procedures were randomized into the ANI group, SPI group and control group. Anaesthesia and intraoperative use of opioids (sufentanil boluses based on body weight) were managed according to a strict protocol. The use of sufentanil was targeted to keep ANI value 50 - 70 in the ANI group, SPI value below individual postinduction baseline value plus 10 points in the SPI group. In the control group, the use of opioids was left at anaesthesiologist's discretion. RESULTS: Additional sufentanil boluses were administered earlier in the ANI and SPI groups in comparison to the control group (3rd dose after 51.8 +- 22.1 vs 52.7 +- 14.8 vs 84.5 +- 24.8 min respectively, p = 0.001; 4th dose after 61.3 +- 30.1 vs 57.2 +- 14.1 vs 120.0 +- 26.2 min, p = 0.003, and 5th dose after 78.8 +- 33.7 vs 74.0 +- 11.6 vs 146.7 +- 23.2 min respectively, p = 0.009). There were no differences in postoperative cortisol levels, time to spontaneous breathing at the end of anaesthesia and postoperative pain scores. CONCLUSIONS: Both ANI and SPI guidance significantly modified intraoperative opiod use, but no modification of postoperative cortisol levels and postoperative pain was observed.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30223 - Anaesthesiology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Minerva Anestesiologica
ISSN
0375-9393
e-ISSN
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Volume of the periodical
85
Issue of the periodical within the volume
12
Country of publishing house
IT - ITALY
Number of pages
8
Pages from-to
1265-1272
UT code for WoS article
000503499600005
EID of the result in the Scopus database
2-s2.0-85076179619