Microsurgical versus endoscopic surgery for non-functioning pituitary adenomas: a retrospective study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F20%3A10418370" target="_blank" >RIV/00179906:_____/20:10418370 - isvavai.cz</a>

Result on the web

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=CexjjX-PUj" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=CexjjX-PUj</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3325/cmj.2020.61.410" target="_blank" >10.3325/cmj.2020.61.410</a>

Result language

angličtina

Original language name

Microsurgical versus endoscopic surgery for non-functioning pituitary adenomas: a retrospective study

Original language description

Aim To compare microsurgical technique (mTSS) and endoscopic technique (eTSS) in the treatment of non-functioning pituitary adenomas (NFPAs). Methods We retrospectively evaluated the charts of 50 patients who underwent either mTSS or eTSS for NFPA in the Department of Neurosurgery, University Hospital Hradec Kralove from 2013 to 2019. We enrolled all patients who were not treated by postoperative adjuvant radiotherapy and who underwent at least two regular postoperative magnetic resonance imaging (MRI) tests. We compared the groups in terms of the extent of resection, surgery duration, blood loss, complication rate, overall clinical effect on the endocrinological and ophthalmological deficit, and postoperative growth pattern of the residual tumor mass. Results The mTSS group had significantly shorter surgical time (75 min vs 127 min, P&lt; 0.001) and lower perioperative blood loss (156 mL vs 256 mL, P=0.027). The groups did not significantly differ in the extent of resection, overall clinical or hormonal effect, and the complication rate. The extent of resection did not correlate with tumor consistency, while the tumor growth rate did not correlate with age or Ki-67 expression. Conclusions There was no major difference between the approaches in surgery radicality or safeness. However, eTSS remains the method of choice due to its potentially higher postoperative preservation of hormonal functions.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30206 - Otorhinolaryngology

Project

<a href="/en/project/NV19-01-00435" target="_blank" >NV19-01-00435: Internexin-alpha in aggressive/fast- and slow growing clinically non-functioning pituitary adenomas</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Croatian Medical Journal

ISSN

0353-9504

e-ISSN

—

Volume of the periodical

61

Issue of the periodical within the volume

5

Country of publishing house

HR - CROATIA

Number of pages

12

Pages from-to

410-421

UT code for WoS article

000589409900004

EID of the result in the Scopus database

2-s2.0-85095677472